Research

Paediatric Cancer Treatment

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Publications

  • Kim H, Calatayud Aristoy C, Guha S, Fernández-Carasa I, Berkowitz L, Carballo-Carbajal I, Ezquerra M, Fernández-Santiago R, Kapahi P, Raya Á, Miranda-Vizuete A, Lizcano JM, Vilà-Ubach M, Caldwell KA, Caldwell GA, Consiglio A and Dalfo E.

    The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against a-Synuclein-Induced Toxicity.

    MOLECULAR NEUROBIOLOGY . 55(9): 7533-7552. Number of citations: 10

    [doi:10.1007/s12035-018-0881-7]

  • Manzanares-Quintela A, Restrepo-Perdomo CA, Botteri G, Castillo H, Pascual-Pastó G, Cano F, Garcia-Alvarez L, Monterrubio C, Ruiz B, Vazquez M, Suñol M, Mora J, Tornero JA, Sosnik A and Carcaboso AM.

    Tissue Compatibility of SN-38-Loaded Anticancer Nanofiber Matrices

    ADVANCED HEALTHCARE MATERIALS . 7(15): . Number of citations: 4

    [doi:10.1002/adhm.201800255]

  • Deng MY, Sill M, Chiang J, Schittenhelm J, Ebinger M, Schuhmann MU, Monoranu CM, Milde T, Wittmann A, Hartmann C, Sommer C, Paulus W, Gärtner J, Brück W, Rüdiger T, Leipold A, Jaunmuktane Z, Brandner S, Giangaspero F, Nozza P, Mora J, Morales-La Madrid A, Cruz-Martínez O, Hansford JR, Pietsch T, Tietze A, Hernáiz-Driever P, Stoler I, Capper D, Korshunov A, Ellison DW, von Deimling A, Pfister SM, Sahm F and Jones DTW.

    Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features

    ACTA NEUROPATHOLOGICA . 136(2): 239-253. Number of citations: 111

    [doi:10.1007/s00401-018-1865-4]

  • Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, Taylor KR, Pemberton HN, Lord CJ, Gutteridge A, Forshew T, Carvalho D, Marshall LV, Qin EY, Ingram WJ, Moore AS, Ng HK, Trabelsi S, H'mida-Ben Brahim D, Entz-Werle N, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Suñol M, Mora J, de Torres C, Cruz-Martínez O, Carcaboso AM, Monje M, Mackay A and Jones C.

    Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

    NATURE MEDICINE . 24(8): 1204-1215. Number of citations: 125

    [doi:10.1038/s41591-018-0086-7]

  • García-Domínguez DJ, Hontecillas-Prieto L, Rodríguez-Núñez P, Pascual-Pastó G, Vilà-Ubach M, García-Mejías R, Robles MJ, Tirado OM, Mora J, Carcaboso AM and de Álava E.

    The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma.

    Oncotarget . 9(59): 31397-31410. Number of citations: 25

    [doi:10.18632/oncotarget.25829]

  • Pérez V, Sampor C, Rey G, Parareda A, Kopp K, Dabezies AP, Dufort G, Zelter M, López JP, Urbieta M, Alcalde-Ruiz E, Català-Mora J, Suñol M, Ossandon D, Fandiño AC, Croxatto JO, de Dávila MTG, Reaman G, Ravindranath Y and Chantada G.

    Treatment of Nonmetastatic Unilateral Retinoblastoma in Children

    JAMA OPHTHALMOLOGY . 136(7): 747-752. Number of citations: 29

    [doi:10.1001/jamaophthalmol.2018.1501]

  • Bukchin A, Pascual-Pastó G, Cuadrado-Vilanova M, Castillo-Ecija H, Monterrubio C, Gene-Olaciregui N, Vilà-Ubach M, Ordeix L, Mora J, Carcaboso AM and Sosnik A.

    Glucosylated nanomicelles target glucose-avid pediatric patient-derived sarcomas

    JOURNAL OF CONTROLLED RELEASE . 276: 59-71. Number of citations: 27

    [doi:10.1016/j.jconrel.2018.02.034]

  • Benitez-Ribas D, Cabezón R, Flórez-Grau G, Molero MC, Puerta P, Guillen-Quesada A, Paco-Mercader S, Carcaboso AM, Santa-Maria Lopez V, Cruz-Martínez O, de Torres C, Salvador N, Juan M, Mora J and Morales-La Madrid A.

    Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

    Frontiers in oncology . 8: 127-127. Number of citations: 31

    [doi:10.3389/fonc.2018.00127]

  • Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popovic M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE and Suvà ML.

    Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

    SCIENCE . 360(6386): 331-335. Number of citations: 415

    [doi:10.1126/science.aao4750]

  • Mora J, Pérez-Jaume S and Cruz-Martínez O.

    Treatment of childhood astrocytomas with irinotecan and cisplatin

    CLINICAL & TRANSLATIONAL ONCOLOGY . 20(4): 500-507. Number of citations: 3

    [doi:10.1007/s12094-017-1741-z]