Research

Paediatric Cancer Treatment

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Publications

  • Sewing AC, Lagerweij T, van Vuurden DG, Meel MH, Veringa SJ, Carcaboso AM, Gaillard PJ, Peter Vandertop W, Wesseling P, Noske D, Kaspers GJ and Hulleman E.

    Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma

    JOURNAL OF NEUROSURGERY-PEDIATRICS . 19(5): 518-530. Number of citations: 23

    [doi:10.3171/2016.9.PEDS16152]

  • Morales-La Madrid A, Santa-María V, Cruz-Martínez O, Mora J, Puerta Roldan P, Guillen-Quesada A, Suñol M, de Torres C, Lassaletta A, Laperriere N, Villà S and Bouffet E.

    Second re-irradiation for DIPG progression, re-considering "old strategies" with new approaches

    CHILDS NERVOUS SYSTEM . 33(5): 849-852. Number of citations: 15

    [doi:10.1007/s00381-017-3352-y]

  • Mohammad F, Weissmann S, Leblanc B, Pandey DP, Højfeldt JW, Comet I, Zheng C, Johansen JV, Rapin N, Porse BT, Tvardovskiy A, Jensen ON, Gene-Olaciregui N, Lavarino C, Suñol M, de Torres C, Mora J, Carcaboso AM and Helin K.

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    NATURE MEDICINE . 23(4): 483-492. Number of citations: 390

    [doi:10.1038/nm.4293]

  • van Zanten SE, Baugh J, Chaney B, De Jongh D, Aliaga ES, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, Bison B, Jones DT, Sturm D, Gielen GH, Jones C, Hulleman E, Calmon R, Castel D, Varlet P, Giraud G, Slavc I, Van Gool S, Jacobs S, Jadrijevic-Cvrlje F, Sumerauer D, Nysom K, Pentikainen V, Kivivuori SM, Leblond P, Entz-Werle N, von Bueren AO, Kattamis A, Hargrave DR, Hauser P, Garami M, Thorarinsdottir HK, Pears J, Gandola L, Rutkauskiene G, Janssens GO, Torsvik IK, Perek-Polnik M, Gil-da-Costa MJ, Zheludkova O, Shats L, Deak L, Kitanovski L, Cruz-Martínez O, Morales-La Madrid A, Holm S, Gerber N, Kebudi R, Grundy R, Lopez-Aguilar E, Zapata-Tarres M, Emmerik J, Hayden T, Bailey S, Biassoni V, Massimino M, Grill J, Vandertop WP, Kaspers GJ, Fouladi M, Kramm CM, van Vuurden DG and members of the SIOPE DIPG Network.

    Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

    JOURNAL OF NEURO-ONCOLOGY . 132(2): 255-266. Number of citations: 40

    [doi:10.1007/s11060-016-2363-y]

  • Janssens GO, Gandola L, Bolle S, Mandeville H, Ramos-Albiac M, van Beek K, Benghiat H, Hoeben B, Morales-La Madrid A, Kortmann RD, Hargrave D, Menten J, Pecori E, Biassoni V, von Bueren AO, van Vuurden DG, Massimino M, Sturm D, Peters M and Kramm CM.

    Survival benefit for patients with diffuse intrinsic pontine glioma (DIPG) undergoing re-irradiation at first progression: A matched-cohort analysis on behalf of the SIOP-E-HGG/DIPG working group.

    EUROPEAN JOURNAL OF CANCER . 73: 38-47. Number of citations: 91

    [doi:10.1016/j.ejca.2016.12.007]

  • Monterrubio C, Paco-Mercader S, Gene-Olaciregui N, Pascual-Pastó G, Vilà-Ubach M, Cuadrado-Vilanova M, Ferrandiz MM, Castillo-Ecija H, Glisoni R, Kuplennik N, Jungbluth A, de Torres C, Lavarino C, Cheung NV, Mora J, Sosnik A and Carcaboso AM.

    Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8

    JOURNAL OF CONTROLLED RELEASE . 255: 108-119. Number of citations: 35

    [doi:10.1016/j.jconrel.2017.04.016]

  • Hennika T, Hu G, Gene-Olaciregui N, Barton KL, Ehteda A, Chitranjan A, Chang C, Gifford AJ, Tsoli M, Ziegler DS, Carcaboso AM and Becher OJ.

    Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

    PLoS One . 12(1): . Number of citations: 130

    [doi:10.1371/journal.pone.0169485]

  • Monsonís Cabedo M, Rives-Solà S, Noguera-Julián A, Urrea M, Cruz-Martínez O and Gene-Giralt A.

    Assessment of anaerobic blood cultures in pediatric oncology patients

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 35(1): 33-36. Number of citations: 5

    [doi:10.1016/j.eimc.2016.04.009]

  • Fang X, Zhou W, Wu Q, Huang Z, Shi Y, Yang K, Chen C, Xie Q, Mack SC, Wang X, Carcaboso AM, Sloan AE, Ouyang G, McLendon RE, Bian XW, Rich JN and Bao S.

    Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

    JOURNAL OF EXPERIMENTAL MEDICINE . 214(1): 245-267. Number of citations: 121

    [doi:10.1084/jem.20151673]

  • Di Cataldo A, Agodi A, Balaguer J, Garaventa A, Barchitta M, Segura V, Bianchi M, Castel V, Castellano A, Cesaro S, Couselo JM, Cruz-Martínez O, D'Angelo P, De Bernardi B, Donat J, de Andoin NG, Hernandez MI, La Spina M, Lillo M, Lopez-Almaraz R, Luksch R, Mastrangelo S, Mateos E, Molina J, Moscheo C, Mura R, Porta F, Russo G, Tondo A, Torrent M, Vetrella S, Villegas JA, Viscardi E, Zanazzo GA and Cañete A.

    Metastatic neuroblastoma in infants: are survival rates excellent only within the stringent framework of clinical trials?

    CLINICAL & TRANSLATIONAL ONCOLOGY . 19(1): 76-83. Number of citations: 9

    [doi:10.1007/s12094-016-1505-1]