Research

Paediatric Cancer Treatment

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Publications

  • Wiese M, Hamdan FH, Kubiak K, Diederichs C, Gielen GH, Nussbaumer G, Carcaboso AM, Hulleman E, Johnsen SA and Kramm CM.

    Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells

    CELL DEATH & DISEASE . 11(8): 673-673. Number of citations: 40

    [doi:10.1038/s41419-020-02800-7]

  • Castillo H, Monterrubio C, Pascual-Pastó G, Gomez-Gonzalez S, Garcia-Dominguez DJ, Hontecillas-Prieto L, Resa-Parés C, Burgeño-Sandoval V, Paco-Mercader S, Gene-Olaciregui N, Vilà-Ubach M, Restrepo-Perdomo C, Cuadrado-Vilanova M, Balaguer-Lluna L, Pérez-Jaume S, Castañeda-Heredia A, Santa-María López V, Roldan-Molina M, Suñol M, de Alava E, Mora J, Lavarino C and Carcaboso AM.

    Treatment-driven selection of chemoresistant Ewing sarcoma tumors with limited drug distribution

    JOURNAL OF CONTROLLED RELEASE . 324: 440-449. Number of citations: 6

    [doi:10.1016/j.jconrel.2020.05.032]

  • Chen KY, Bush K, Klein RH, Cervantes V, Lewis N, Naqvi A, Carcaboso AM, Lechpammer M and Knoepfler PS.

    Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling

    Communications Biology . 3(1): 363-363. Number of citations: 32

    [doi:10.1038/s42003-020-1076-0]

  • Bossacoma F, Cuadrado-Vilanova M, Vinent-Genestar J, Correa MG, Gavrus D, Castillo H, Català-Mora J, Mora J, Schaiquevich P, Chantada G and Carcaboso AM.

    Optimizing the storage of chemotherapeutics for ophthalmic oncology: stability of topotecan solution for intravitreal injection

    OPHTHALMIC GENETICS . 41(4): 397-400. Number of citations: 1

    [doi:10.1080/13816810.2020.1776336]

  • Fernández-Rodríguez J, Morales-La Madrid A, Gel B, Castañeda-Heredia A, Salvador-Hernandez H, Martínez-Iniesta M, Moutinho C, Morata J, Heyn H, Blanco I, Creus-Bachiller E, Capella G, Farré L, Vidal A, Soldado F, Krauel L, Suñol M, Serra E, Villanueva A and Lázaro C.

    Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor

    THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY . 12: . Number of citations: 5

    [doi:10.1177/1758835920929579]

  • Meel MH, de Gooijer MC, Metselaar DS, Sewing ACP, Zwaan K, Waranecki P, Breur M, Buil LCM, Lagerweij T, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Carcaboso AM, Bugiani M, Phoenix TN, van Tellingen O, van Vuurden DG, Kaspers GJL and Hulleman E.

    Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma

    CLINICAL CANCER RESEARCH . 26(13): 3319-3332. Number of citations: 42

    [doi:10.1158/1078-0432.CCR-19-3538]

  • Pinto EM, Figueiredo BC, Chen W, Galvao HCR, Formiga MN, Fragoso MCBV, Ashton-Prolla P, Ribeiro EMSF, Felix G, Costa TEB, Savage SA, Yeager M, Palmero EI, Volc S, Salvador-Hernandez H, Fuster-Soler JL, Lavarino C, Chantada G, Vaur D, Odone-Filho V, Brugières L, Else T, Stoffel EM, Maxwell KN, Achatz MI, Kowalski L, de Andrade KC, Pappo A, Letouze E, Latronico AC, Mendonca BB, Almeida MQ, Brondani VB, Bittar CM, Soares EWS, Mathias C, Ramos CRN, Machado M, Zhou W, Jones K, Vogt A, Klincha PP, Santiago KM, Komechen H, Paraizo MM, Parise IZS, Hamilton KV, Wang J, Rampersaud E, Clay MR, Murphy AJ, Lalli E, Nichols KE, Ribeiro RC, Rodriguez-Galindo C, Korbonits M, Zhang J, Thomas MG, Connelly JP, Pruett-Miller S, Diekmann Y, Neale G, Wu G and Zambetti GP.

    XAF1 as a modifier of p53 function and cancer susceptibility.

    Science Advances . 6(26): . Number of citations: 39

    [doi:10.1126/sciadv.aba3231]

  • Deligne C, Hachani J, Duban-Deweer S, Meignan S, Leblond P, Carcaboso AM, Sano Y, Shimizu F, Kanda T, Gosselet F, Dehouck MP and Mysiorek C.

    Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

    Fluids and Barriers of the CNS . 17(1): 37-37. Number of citations: 32

    [doi:10.1186/s12987-020-00198-0]

  • Galardi A, Colletti M, Lavarello C, Paolo VD, Mascio P, Russo I, Cozza R, Romanzo A, Valente P, Vito R, Pascucci L, Peinado H, Carcaboso AM, Petretto A, Locatelli F and Giannatale AD.

    Proteomic Profiling of Retinoblastoma-Derived Exosomes Reveals Potential Biomarkers of Vitreous Seeding

    Cancers . 12(6): . Number of citations: 35

    [doi:10.3390/cancers12061555]

  • Nobre L, Zapotocky M, Ramaswamy V, Ryall S, Bennett J, Alderete D, Balaguer Guill J, Baroni L, Bartels U, Bavle A, Bornhorst M, Boue DR, Canete A, Chintagumpala M, Coven SL, Cruz-Martínez O, Dahiya S, Dirks P, Dunkel IJ, Eisenstat D, Faure Conter C, Finch E, Finlay JL, Frappaz D, Garre ML, Gauvain K, Bechensteen AG, Hansford JR, Harting I, Hauser P, Hazrati LN, Huang A, Injac SG, Iurilli V, Karajannis M, Kaur G, Kyncl M, Krskova L, Laperriere N, Larouche V, Lassaletta A, Leary S, Lin F, Mascelli S, McKeown T, Milde T, Morales-La Madrid A, Morana G, Morse H, Mushtaq N, Osorio DS, Packer R, Pavelka Z, Quiroga-Cantero E, Rutka J, Sabel M, Salgado D, Solano P, Sterba J, Su J, Sumerauer D, Taylor MD, Toledano H, Tsang DS, Valente Fernandes M, van Landeghem F, van Tilburg CM, Wilson B, Witt O, Zamecnik J, Bouffet E, Hawkins C and Tabori U.

    Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition

    JCO Precision Oncology . 4: 561-571. Number of citations: 90

    [doi:10.1200/PO.19.00298]