People / Staff

Sandra Castillo Diez

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Publications

  • Angulo-Urarte A, Casado P, CastilloSD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR and Graupera M.

    Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.

    NATURE COMMUNICATIONS . 9(1): 4826-4826. Number of citations: 49

    [doi:10.1038/s41467-018-07172-3]

  • Berenjeno IM, Piñeiro R, CastilloSD, Pearce W, McGranahan N, Dewhurst SM, Meniel V, Birkbak NJ, Lau E, Sansregret L, Morelli D, Kanu N, Srinivas S, Graupera M, Parker VER, Montgomery KG, Moniz LS, Scudamore CL, Phillips WA, Semple RK, Clarke A, Swanton C and Vanhaesebroeck B.

    Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

    NATURE COMMUNICATIONS . 8(1): 1773-1773. Number of citations: 53

    [doi:10.1038/s41467-017-02002-4]

  • CastilloSD, Vanhaesebroeck B and Sebire NJ.

    Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies.

    JOURNAL OF PATHOLOGY . 240(4): 387-396. Number of citations: 16

    [doi:10.1002/path.4802]

  • CastilloSD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M and Vanhaesebroeck B.

    Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

    SCIENCE TRANSLATIONAL MEDICINE . 8(332): . Number of citations: 124

    [doi:10.1126/scitranslmed.aad9982]

  • CastilloSD, Perosanz X, Ressler AK, Ivars M, Rodriguez J, Rovira-Zurriaga C, Nola EM, Llena J, Grego-Bessa J, Roldan-Molina M, Arnau R, Martínez-Romero A, Barber-Martínez de la Torre I, Miguel Bejarano Serrano, Vicente-Villa MA, Celis-Passini V, Salvador-Hernandez H, Mora J, Marchuk DA, Baselga E and Graupera M.

    Somatic uniparental disomy of PTEN in endothelial cells causes vascular malformations in patients with PTEN Hamartoma Tumor Syndrome.

    CANCER DISCOVERY . : .

    [doi:10.1158/2159-8290.CD-24-0807]