Publications
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Conduit SE, Pearce W, Bhamra A, Bilanges B, Bozal-Basterra L, Foukas LC, Cobbaut M, CastilloSD, Danesh MA, Adil M, Carracedo A, Graupera M, McDonald NQ, Parker PJ, Cutillas PR, Surinova S and Vanhaesebroeck B.
A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease.
NATURE COMMUNICATIONS . 15(1): 7181-7181.
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Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, CastilloSD, Sardina JL, Valencia A and Javierre BM.
p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
NATURE COMMUNICATIONS . 15(1): 2821-2821. Number of citations: 4
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Cerdà P, CastilloSD, Aguilera C, Iriarte A, Rocamora JL, Larrinaga AM, Viñals F, Graupera M and Riera-Mestre A.
New genetic drivers in hemorrhagic hereditary telangiectasia.
EUROPEAN JOURNAL OF INTERNAL MEDICINE . 119: 99-108. Number of citations: 3
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Kobialka P, Llena J, Deleyto-Seldas N, Munar-Gelabert M, Dengra JA, Villacampa P, Albinyà-Pedrós A, Muixi L, Andrade J, van Splunder H, Angulo-Urarte A, Potente M, Grego-Bessa J, CastilloSD, Vanhaesebroeck B, Efeyan A and Graupera M.
PI3K-C2ß limits mTORC1 signaling and angiogenic growth.
SCIENCE SIGNALING . 16(813): . Number of citations: 1
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Petkova M, Kraft M, Stritt S, Martinez-Corral I, Ortsäter H, Vanlandewijck M, Jakic B, Baselga E, CastilloSD, Graupera M, Betsholtz C and Mäkinen T.
Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation.
JOURNAL OF EXPERIMENTAL MEDICINE . 220(4): . Number of citations: 19
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Kobialka P, Sabata H, Vilalta O, Gouveia L, Angulo-Urarte A, Muixí L, Zanoncello J, Muñoz-Aznar O, Gene-Olaciregui N, Fanlo L, Esteve-Codina A, Lavarino C, Javierre BM, Celis-Passini V, Rovira-Zurriaga C, López-Fernández S, Baselga E, Mora J, CastilloSD and Graupera M.
The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.
EMBO Molecular Medicine . 14(7): . Number of citations: 27
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Monelli E, Villacampa P, Zabala-Letona A, Martinez-Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama-Perez P, Osorio-Conles O, Muixi L, Martinez-Gonzalez A, CastilloSD, Martín-Martín N, Castel P, Valcarcel-Jimenez L, Garcia-Gonzalez I, Villena JA, Fernandez-Ruiz S, Serra D, Herrero L, Benedito R, Garcia-Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A and Graupera M.
Angiocrine polyamine production regulates adiposity.
Nature Metabolism . 4(3): 327-343. Number of citations: 34
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Crainiciuc G, Palomino-Segura M, Molina-Moreno M, Sicilia J, Aragones DG, Li JLY, Madurga R, Adrover JM, Aroca-Crevillén A, Martin-Salamanca S, Del Valle AS, CastilloSD, Welch HCE, Soehnlein O, Graupera M, Sánchez-Cabo F, Zarbock A, Smithgall TE, Di Pilato M, Mempel TR, Tharaux PL, González SF, Ayuso-Sacido A, Ng LG, Calvo GF, González-Díaz I, Díaz-de-María F and Hidalgo A.
Behavioural immune landscapes of inflammation.
Nature . 601(7893): 415-421. Number of citations: 57
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Martinez-Corral I, Zhang Y, Petkova M, Ortsäter H, Sjöberg S, CastilloSD, Brouillard P, Libbrecht L, Saur D, Graupera M, Alitalo K, Boon L, Vikkula M and Mäkinen T.
Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
NATURE COMMUNICATIONS . 11(1): 2869-2869. Number of citations: 59
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CastilloSD, Baselga E and Graupera M.
PIK3CA mutations in vascular malformations.
CURRENT OPINION IN HEMATOLOGY . 26(3): 170-178. Number of citations: 32