Persones / Equip Humà

Sandra Castillo Diez

Buscador de publicacions

Publicacions

  • Conduit SE, Pearce W, Bhamra A, Bilanges B, Bozal-Basterra L, Foukas LC, Cobbaut M, CastilloSD, Danesh MA, Adil M, Carracedo A, Graupera M, McDonald NQ, Parker PJ, Cutillas PR, Surinova S and Vanhaesebroeck B.

    A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease.

    NATURE COMMUNICATIONS . 15(1): 7181-7181.

    [doi:10.1038/s41467-024-51354-1]

  • Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, CastilloSD, Sardina JL, Valencia A and Javierre BM.

    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.

    NATURE COMMUNICATIONS . 15(1): 2821-2821.

    [doi:10.1038/s41467-024-46666-1]

  • Cerdà P, CastilloSD, Aguilera C, Iriarte A, Rocamora JL, Larrinaga AM, Viñals F, Graupera M and Riera-Mestre A.

    New genetic drivers in hemorrhagic hereditary telangiectasia.

    EUROPEAN JOURNAL OF INTERNAL MEDICINE . 119: 99-108.

    [doi:10.1016/j.ejim.2023.08.024]

  • Kobialka P, Llena J, Deleyto-Seldas N, Munar-Gelabert M, Dengra JA, Villacampa P, Albinyà-Pedrós A, Muixi L, Andrade J, van Splunder H, Angulo-Urarte A, Potente M, Grego-Bessa J, CastilloSD, Vanhaesebroeck B, Efeyan A and Graupera M.

    PI3K-C2ß limits mTORC1 signaling and angiogenic growth.

    SCIENCE SIGNALING . 16(813): .

    [doi:10.1126/scisignal.adg1913]

  • Petkova M, Kraft M, Stritt S, Martinez-Corral I, Ortsäter H, Vanlandewijck M, Jakic B, Baselga E, CastilloSD, Graupera M, Betsholtz C and Mäkinen T.

    Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation.

    JOURNAL OF EXPERIMENTAL MEDICINE . 220(4): . Nº de cites: 19

    [doi:10.1084/jem.20220741]

  • Kobialka P, Sabata H, Vilalta O, Gouveia L, Angulo-Urarte A, Muixí L, Zanoncello J, Muñoz-Aznar O, Gene-Olaciregui N, Fanlo L, Esteve-Codina A, Lavarino C, Javierre BM, Celis-Passini V, Rovira-Zurriaga C, López-Fernández S, Baselga E, Mora J, CastilloSD and Graupera M.

    The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.

    EMBO Molecular Medicine . 14(7): . Nº de cites: 27

    [doi:10.15252/emmm.202115619]

  • Monelli E, Villacampa P, Zabala-Letona A, Martinez-Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama-Perez P, Osorio-Conles O, Muixi L, Martinez-Gonzalez A, CastilloSD, Martín-Martín N, Castel P, Valcarcel-Jimenez L, Garcia-Gonzalez I, Villena JA, Fernandez-Ruiz S, Serra D, Herrero L, Benedito R, Garcia-Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A and Graupera M.

    Angiocrine polyamine production regulates adiposity.

    Nature Metabolism . 4(3): 327-343.

    [doi:10.1038/s42255-022-00544-6]

  • Crainiciuc G, Palomino-Segura M, Molina-Moreno M, Sicilia J, Aragones DG, Li JLY, Madurga R, Adrover JM, Aroca-Crevillén A, Martin-Salamanca S, Del Valle AS, CastilloSD, Welch HCE, Soehnlein O, Graupera M, Sánchez-Cabo F, Zarbock A, Smithgall TE, Di Pilato M, Mempel TR, Tharaux PL, González SF, Ayuso-Sacido A, Ng LG, Calvo GF, González-Díaz I, Díaz-de-María F and Hidalgo A.

    Behavioural immune landscapes of inflammation.

    Nature . 601(7893): 415-421.

    [doi:10.1038/s41586-021-04263-y]

  • Martinez-Corral I, Zhang Y, Petkova M, Ortsäter H, Sjöberg S, CastilloSD, Brouillard P, Libbrecht L, Saur D, Graupera M, Alitalo K, Boon L, Vikkula M and Mäkinen T.

    Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.

    NATURE COMMUNICATIONS . 11(1): 2869-2869.

    [doi:10.1038/s41467-020-16496-y]

  • CastilloSD, Baselga E and Graupera M.

    PIK3CA mutations in vascular malformations.

    CURRENT OPINION IN HEMATOLOGY . 26(3): 170-178.

    [doi:10.1097/MOH.0000000000000496]