Research

Leukaemia and Paediatric Haematology Disorders

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Publications

  • Gutierrez-Camino A, Caron M, Richer C, Fuchs C, Illarregi U, Poncelet L, St-Onge P, Bataille AR, Tremblay-Dauphinais P, Lopez-Lopez E, Camós-Guijosa M, Ramirez-Orellana M, Astigarraga I, Lécuyer É, Bourque G, Martin-Guerrero I and Sinnett D.

    CircRNAome of Childhood Acute Lymphoblastic Leukemia: Deciphering Subtype-Specific Expression Profiles and Involvement in TCF3::PBX1 ALL

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 25(3): .

    [doi:10.3390/ijms25031477]

  • Velasco-Hernandez, T, Trincado, JL, Vinyoles, M, Closa, A, Martínez-Moreno, A, Gutiérrez-Agüera, F, Molina, O, Rodríguez-Cortez, VC, Ximeno-Parpal, P, Fernández-Fuentes, N, Petazzi, P, Beneyto-Calabuig, S, Velten, L, Romecin, P, Casquero, R, Abollo-Jiménez, F, de la Guardia, RD, Lorden, P, Bataller, A, Lapillonne, H, Stam, RW, Vives, S, Torrebadell-Burriel M, Fuster, JL, Bueno, C, Sarry, JE, Eyras, E, Heyn, H and Menéndez, P.

    Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells

    hemasphere . 8(2): . Number of citations: 2

    [doi:10.1002/hem3.45]

  • Ramamoorthy S, Lebrecht D, Schanze D, Schanze I, Wieland I, Andrieux G, Metzger P, Hess M, Albert MH, Borkhardt A, Bresters D, Buechner J, Català-Temprano A, De Haas V, Dworzak M, Erlacher M, Hasle H, Jahnukainen K, Locatelli F, Masetti R, Stary J, Turkiewicz D, Vinci L, Wlodarski MW, Yoshimi A, Boerries M, Niemeyer CM, Zenker M and Flotho C.

    Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup

    BRITISH JOURNAL OF HAEMATOLOGY . 204(2): 595-605. Number of citations: 1

    [doi:10.1111/bjh.19190]

  • Rossig C, Pearson AD, Vassal G, Scobie N, Bird N, Blanc P, Vormoor HJ, Calkoen FG, Locatelli F, Bufalo FD, Rives-Solà S, Jacoby E, Balduzzi A, Bourquin JP and Baruchel A.

    Chimeric Antigen Receptor (CAR) T-Cell Products for Pediatric Cancers: Why Alternative Development Paths Are Needed.

    JOURNAL OF CLINICAL ONCOLOGY . 42(3): 253-257. Number of citations: 4

    [doi:10.1200/JCO.23.01314]

  • Molinos-Quintana Á, Alonso-Saladrigues A, Herrero B, Caballero-Velázquez T, Galán-Gómez V, Panesso M, Torrebadell-Burriel M, Delgado-Serrano J, Pérez de Soto C, Faura A, González-Martínez B, Castillo-Robleda A, Diaz-de-Heredia C, Pérez-Martínez A, Pérez-Hurtado JM, Rives-Solà S and Pérez-Simón JA.

    Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring

    FRONTIERS IN IMMUNOLOGY . 14: 1280580-1280580. Number of citations: 5

    [doi:10.3389/fimmu.2023.1280580]

  • Molina O, Ortega-Sabater C, Thampi N, Fernández-Fuentes N, Guerrero-Murillo M, Martínez-Moreno A, Vinyoles M, Velasco-Hernández T, Bueno C, Trincado JL, Granada I, Campos D, Giménez C, Boer JM, den Boer ML, Calvo GF, Camós-Guijosa M, Fuster JL, Velasco P, Ballerini P, Locatelli F, Mullighan CG, Spierings DCJ, Foijer F, Pérez-García VM and Menéndez P.

    Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression

    EMBO Molecular Medicine . 16(1): 64-92. Number of citations: 2

    [doi:10.1038/s44321-023-00006-w]

  • Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, Díez P, Bakardjieva M, Stancikova J, Raabe J, Neumann J, Schwenk S, Arpesella L, Stuchly J, Benes V, García Valiente R, Fernández García J, Carsetti R, Piano Mortari E, Català-Temprano A, de la Calle O, Sogkas G, Neven B, Rieux-Laucat F, Magerus A, Neth O, Olbrich P, Voll RE, Alsina L, Allende LM, Gonzalez-Granado LI, Böhler C, Thiel J, Venhoff N, Lorenzetti R, Warnatz K, Unger S, Seidl M, Mielenz D, Schneider P, Ehl S, Rensing-Ehl A, Smulski CR and Rizzi M.

    Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells

    Science immunology . 9(91): .

    [doi:10.1126/sciimmunol.adj5948]

  • Bandini P, Borràs N, Berrueco R, Gassiot S, Martin-Fernandez L, Sarrate E, Comes N, Ramírez L, Hobeich C, Vidal F and Corrales I.

    Gaining Insights into Inherited Bleeding Disorders of Complex Etiology in Pediatric Patients: Whole-Exome Sequencing as First-Line Investigation Tool

    THROMBOSIS AND HAEMOSTASIS . 124(7): 628-640.

    [doi:10.1055/s-0043-1778070]

  • Rives-Solà S.

    Central nervous system therapy in acute lymphoblastic leukemia: no more, no less.

    HAEMATOLOGICA . 108(12): 3193-3194.

    [doi:10.3324/haematol.2023.283275]

  • Bueno C, Torres-Ruíz R, Velasco-Hernandez T, Molina O, Petazzi P, Martinez-Moreno A, Rodríguez-Cortez VC, Vinyoles M, Cantilena S, Williams O, Vega-García N, Rodriguez-Perales S, Segovia JC, Quintana-Bustamante O, Roy A, Meyer C, Marschalek R, Smith A, Milne TA, Fraga MF, Tejedor JRR and Menendez P.

    A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features

    Blood . 142(20): 1752-1756. Number of citations: 2

    [doi:10.1182/blood.2023020858]