Research

Pharmacological targets in inflammation and metabolic diseases

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Publications

  • Jurado-Aguilar J, Barroso E, Bernard M, Zhang M, Peyman M, Rada P, Valverde ÁM, Wahli W, Palomer FX and Vazquez M.

    GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-ß1/SMAD3 pathway

    METABOLISM-CLINICAL AND EXPERIMENTAL . 152: 155772-155772. Number of citations: 9

    [doi:10.1016/j.metabol.2023.155772]

  • Peyman M, Barroso E, Turcu AL, Estrany F Jr, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, Palomer FX, Galdeano C, Vázquez S and Vazquez M.

    Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress

    BIOMEDICINE & PHARMACOTHERAPY . 168: 115667-115667. Number of citations: 3

    [doi:10.1016/j.biopha.2023.115667]

  • Barroso E, Díaz M, Reguera AC, Peyman M, Balsinde J, Jurado-Aguilar J, Zhang M, Rostami A, Palomer FX, Ibañez-Toda L and Vazquez M.

    CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns

    CELL COMMUNICATION AND SIGNALING . 21(1): 326-326. Number of citations: 1

    [doi:10.1186/s12964-023-01352-5]

  • Zhang M, Barroso E, Ruart M, Peña L, Peyman M, Aguilar-Recarte D, Montori M, Rada P, Cugat C, Montironi C, Zarei M, Jurado-Aguilar J, Camins A, Balsinde J, Valverde ÁM, Wahli W, Palomer FX and Vazquez M.

    Elafibranor upregulates the EMT-inducer S100A4 via PPARß/d

    BIOMEDICINE & PHARMACOTHERAPY . 167: 115623-115623. Number of citations: 6

    [doi:10.1016/j.biopha.2023.115623]

  • Zhang M, Bagán A, Martínez D, Barroso E, Palomer FX, Vázquez S, Escolano C and Vazquez M.

    Design and Synthesis of AMPK Activators and GDF15 Inducers

    Molecules . 28(14): .

    [doi:10.3390/molecules28145468]

  • Barroso E, Montori M, Wahli W, Palomer FX and Vazquez M.

    Striking a gut-liver balance for the antidiabetic effects of metformin

    TRENDS IN PHARMACOLOGICAL SCIENCES . 44(7): 457-473. Number of citations: 5

    [doi:10.1016/j.tips.2023.04.004]

  • Aguilar-Recarte D, Barroso E, Zhang M, Rada P, Pizarro J, Peña L, Palomer FX, Valverde ÁM, Wahli W and Vazquez M.

    A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.

    PHARMACOLOGICAL RESEARCH . 187: 106578-106578. Number of citations: 18

    [doi:10.1016/j.phrs.2022.106578]

  • Sepúlveda-Fragoso V, Alexandre-Santos B, Barreto-Reis E, Fernandes T, Oliveira EM, Cavalcanti SDNV, Atella GC, Miranda-Alves L, Vazquez M, Nóbrega ACLD, Frantz EDC and Magliano DC.

    Comparison between aerobic exercise training and enalapril treatment as tools to improve diet-induced metabolic-associated fatty liver disease: Effects on endoplasmic reticulum stress markers

    LIFE SCIENCES . 311(Pt A): 121136-121136. Number of citations: 4

    [doi:10.1016/j.lfs.2022.121136]

  • Aguilar-Recarte D, Barroso E, Palomer FX, Wahli W and Vazquez M.

    Knocking on GDF15?s door for the treatment of type 2 diabetes mellitus

    TRENDS IN ENDOCRINOLOGY AND METABOLISM . 33(11): 741-754. Number of citations: 20

    [doi:10.1016/j.tem.2022.08.004]

  • Espinosa-Jiménez T, Busquets O, Cano A, Sánchez-López E, Verdaguer E, Parcerisas A, Olloquequi J, Auladell C, Folch J, Wahli W, Vazquez M, Camins A and Ettcheto M.

    Peroxisomal Proliferator-Activated Receptor ß/d Deficiency Induces Cognitive Alterations.

    FRONTIERS IN PHARMACOLOGY . 13: 902047-902047. Number of citations: 2

    [doi:10.3389/fphar.2022.902047]