People / Staff

Francesc Villarroya Gombau

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Publications

  • Giralt A, Hondares E, Villena JA, Ribas F, Díaz-Delfín J, Giralt M, Iglesias R and Villarroya-Gombau F.

    Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype.

    JOURNAL OF BIOLOGICAL CHEMISTRY . 286(19): 16958-16966. Number of citations: 179

    [doi:10.1074/jbc.M110.202390]

  • Planavila A, Iglesias R, Giralt M and Villarroya-Gombau F.

    Sirt1 acts in association with PPARa to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.

    CARDIOVASCULAR RESEARCH . 90(2): 276-284. Number of citations: 260

    [doi:10.1093/cvr/cvq376]

  • Domingo P, Torres-Torronteras J, Pomar V, Giralt M, Domingo JC, Gutierrez Mdel M, Gallego-Escuredo JM, Mateo MG, Cano-Soldado P, Fernandez I, Pastor-Anglada M, Vidal F, Villarroya-Gombau F, Andreu A and Marti R.

    Uridine metabolism in HIV-1-infected patients: effect of infection, of antiretroviral therapy and of HIV-1/ART-associated lipodystrophy syndrome.

    PLoS One . 5(11): . Number of citations: 10

    [doi:10.1371/journal.pone.0013896]

  • Gallego-Escuredo JM, Del Mar Gutierrez M, Diaz-Delfin J, Domingo JC, Mateo MG, Domingo P, Giralt M and Villarroya-Gombau F.

    Differential effects of efavirenz and lopinavir/ritonavir on human adipocyte differentiation, gene expression and release of adipokines and pro-inflammatory cytokines.

    CURR HIV RES . 8(7): 545-553. Number of citations: 45

    [doi:10.2174/157016210793499222]

  • Hondares E, Rosell M, Gonzalez FJ, Giralt M, Iglesias R and Villarroya-Gombau F.

    Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

    CELL METABOLISM . 11(3): 206-212. Number of citations: 293

    [doi:10.1016/j.cmet.2010.02.001]

  • Villarroya-Gombau F, Domingo P and Giralt M.

    Drug-induced lipotoxicity: lipodystrophy associated with HIV-1 infection and antiretroviral treatment.

    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS . 1801(3): 392-399. Number of citations: 72

    [doi:10.1016/j.bbalip.2009.09.018]

  • Villarroya-Terrade J, Giralt M and Villarroya-Gombau F.

    Mitochondrial DNA: an up-and-coming actor in white adipose tissue pathophysiology.

    Obesity . 17(10): 1814-1820. Number of citations: 31

    [doi:10.1038/oby.2009.152]

  • Amat R, Planavila A, Chen SL, Iglesias R, Giralt M and Villarroya-Gombau F.

    SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.

    JOURNAL OF BIOLOGICAL CHEMISTRY . 284(33): 21872-21880. Number of citations: 185

    [doi:10.1074/jbc.M109.022749]

  • Camara Y, Mampel T, Armengol J, Villarroya-Gombau F and Dejean L.

    UCP3 expression in liver modulates gene expression and oxidative metabolism in response to fatty acids, and sensitizes mitochondria to permeability transition.

    CELL PHYSIOL BIOCHEM . 24(3-4): 243-252. Number of citations: 18

    [doi:10.1159/000233249]

  • Villarroya-Gombau F, Bocos C, Giralt M, Pilar Ramos M, Herrera E, Sevillano J, Gual M, Rosell M and Iglesias R.

    Pharmacological and gene modification-based models for studying the impact of perinatal metabolic disturbances in adult life.

    Advances in Experimental Medicine and Biology . 646: 141-148. Number of citations: 3

    [doi:10.1007/978-1-4020-9173-5_16]