F. Xavier Palomer Tarridas
Investigador
Research line:
Diabetic cardiomyopathy
The researcher F. Xavier Palomer Tarridas graduated in Biology in 1995 from the University of Barcelona. In 1998, after receiving a grant from the Ministry of Education and Science, the Researcher began his doctoral studies at the Institute of Molecular Biology in Barcelona (IBMB-CSIC), obtaining his title of Doctor of Biology by the same University of Barcelona in 2002. During that period, he spent a four-month pre-doctoral stay at the Plant Research International technology center in Wageningen (Netherlands), thanks to a BAC grant awarded by UNESCO.
Between 2002 and 2005, the Researcher spent a post-doctoral stay at the current Biomedical Research Institute of the Hospital de la Santa Creu i Sant Pau in Barcelona, where he began the study of metabolic diseases such as type 2 diabetes (DM2) and obesity, but also of autoimmune origin (type 1 diabetes, DM1), both from a clinical and basic perspective.
In 2006, he obtained a post-doctoral contract from the Juan de la Cierva Program (Ministry of Education and Science) to join the research group of Dr. Manuel Vázquez Carrera, of the Department of Pharmacology, Toxicology and Therapeutic Chemistry of the Faculty of Pharmacy and Food Sciences of the University of Barcelona. Between 2008 and 2015 he pursued these post-doctoral studies in the same Department, thanks to the granting of a post-doctoral contract by CIBERDEM (Carlos III Health Institute). In this center, the Researcher continued the study of metabolic diseases with an inflammatory background (obesity and DM2), also initiating research within the line of diabetic cardiomyopathy, which is currently still the subject of his main line of research.
Since 2015 he has been an Associate Professor at the University of Barcelona in the same Department of Pharmacology, Toxicology and Therapeutic Chemistry.
Last Publications
- Rostami A, Palomer FX, Pizarro J, Barroso E, Valenzuela-Alcaraz BI, Fàtima Crispi Brillas, Nistal JF, Hurlé MA, García R, Wahli W and Vazquez M PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy. PHARMACOLOGICAL RESEARCH . 210: 107515-107515.
- Barroso E, Jurado-Aguilar J, Wahli W, Palomer FX and Vazquez M Increased hepatic gluconeogenesis and type 2 diabetes mellitus. TRENDS IN ENDOCRINOLOGY AND METABOLISM . 35(12): 1062-1077.
- Zhang M, Barroso E, Peña L, Rada P, Valverde ÁM, Wahli W, Palomer FX and Vazquez M PPARß/d attenuates hepatic fibrosis by reducing SMAD3 phosphorylation and p300 levels via AMPK in hepatic stellate cells. BIOMEDICINE & PHARMACOTHERAPY . 179: 117303-117303.
News
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New Therapeutic Targets to Fight Type 2 Diabetes
A study led by Dr Manuel Vázquez-Carreras presents an integrative view of the most outstanding advances in understanding this process and helping to identify new pharmacological targets in the fight against type 2 diabetes mellitus.
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CDF15 cytokine, a promising therapeutic target against type 2 diabetes
A team led by Dr. Manuel Vázquez-Carrera, from the Institut de Recerca Sant Joan de Déu and professor Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine (IBUB) of the UB, has conducted a review study on the Growth Differentiation Factor 15 (GDF15) -a protein expressed under physiological stress conditions- and its potential impact on the treatment for type 2 diabetes.