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News

A drug capable of simultaneously targeting three different therapeutic targets is designed.

The study, published in the journal Bioorganic Chemistry, presents a proof of concept for this innovative triple-effect compound, which has been successfully applied to breast cancer cells. According to experts, this therapy has "high potential for the treatment of complex diseases such as cancer or diabetes.

  1. Researchers discover a new promising strategy to halt the progression of liver fibrosis

    The new work, published in the journal Biomedicine & Pharmacotherapy, has been led by Manuel Vázquez Carrera, head of the research group Pharmacological Targets in Inflammation and Metabolic Diseases at the Sant Joan de Déu Research Institute (IRSJD) and the Biomedical Research Centre in Diabetes and Associated Metabolic Diseases (CIBERDEM) at the University of Barcelona.

  2. Research in Pitt-Hopkins at Sant Joan de Déu, a neurodevelopmental disorder

    Dr. Judith Armstrong initiates a project to understand why patients with mutations in different genes present the same clinical features as Rett syndrome.

  1. International travel affects gut microbiota

    A collaborative study between the Institut de Recerca Sant Joan de Déu (IRSJD) and the Institut d'Investigació i Innovació Parc Taulí (I3PT) demonstrates that traveling and being exposed to new people, traditions, cultures, and unfamiliar foods can change gut microbiota and its diversity.

  2. A Predictive Tool for Personalizing Psychosis Treatment

    Dr. Susana Ochoa from the Sant Joan de Déu Research Institute · Parc Sanitari Sant Joan de Déu leads a European project to offer personalized metacognitive training for people with psychosis by developing a learning algorithm.

  3. A potential therapeutic target has been discovered for the rare metabolic disease PMM2-CDG

    The collaboration of three research groups has made it possible to identify cellular and molecular pathways affected in patients with PMM2-CDG through the development of a transcriptomic data analysis technology using patient-derived fibroblasts.

  4. New discoveries about the EWS-FLI oncogene involved in the development of Ewing's tumor

    Researchers from IRSJD · SJD Barcelona Children’s Hospital and IRB Barcelona have successfully developed Drosophila models expressing the EWS-FLI oncogene at varying levels, overcoming previous toxicity challenges and enabling detailed study of Ewing sarcoma's oncogenic pathways.

  5. Preg-MEDAS questionnaire: questions for a healthier pregnancy

    A study conducted by IRSJD and IDIBAPS introduces the new preg-MEDAS questionnaire, which measures the positive impact of the Mediterranean diet on pregnant women. The study demonstrated that women following the Mediterranean diet significantly reduced their blood pressure.

  6. New Therapeutic Targets to Fight Type 2 Diabetes

    A study led by Dr Manuel Vázquez-Carreras presents an integrative view of the most outstanding advances in understanding this process and helping to identify new pharmacological targets in the fight against type 2 diabetes mellitus.