Research

Paediatric Cancer Epigenetics

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Publications

  • Lorito N, Subbiani A, Smiriglia A, Bacci M, Bonechi F, Tronci L, Romano E, Corrado A, Longo DL, Iozzo M, Ippolito L, Comito G, Giannoni E, Meattini I, Avgustinova A, Chiarugi P, Bachi A and Morandi A.

    FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.

    EMBO Molecular Medicine . 16(7): 1533-1559. Number of citations: 4

    [doi:10.1038/s44321-024-00090-6]

  • Sanchez-Guixe E, Muiños F, Pinheiro-Santin M, González-Huici V, Rodriguez-Hernandez CJ, Avgustinova A, Lavarino C, González- Pérez A, Mora J and López-Bigas N.

    Origins of Second Malignancies in Children and Mutational Footprint of Chemotherapy in Normal Tissues

    CANCER DISCOVERY . 14(6): 953-964. Number of citations: 4

    [doi:10.1158/2159-8290.CD-23-1186]

  • Llorente A, Blasco MT, Espuny I, Guiu M, Ballaré C, Blanco E, Caballé A, Bellmunt A, Salvador F, Morales A, Nuñez M, Loren G, Imbastari F, Fidalgo M, Figueras-Puig C, Gibler P, Graupera M, Monteiro F, Riera A, Holen I, Avgustinova A, Di Croce L and Gomis RR.

    MAF amplification licenses ERa through epigenetic remodelling to drive breast cancer metastasis

    NATURE CELL BIOLOGY . : 1833-1847. Number of citations: 1

    [doi:10.1038/s41556-023-01281-y]

  • Figuerola-Bou E, Rios-Astorch C, Blanco E, Sanchez-Jimenez M, Táboas-Outón P, Fernandez-Isern G, Gomez-Gonzalez S, Muñoz-Aznar O, Castellano P, Pérez-Jaume S, Prada-Varela E, Mateo-Lozano S, Riggi N, Avgustinova A, Lavarino C, Di Croce L, Sánchez-Molina S and Mora J.

    KDM6 demethylases mediate EWSR1-FLI1-driven oncogenic transformation in Ewing Sarcoma

    Biorxiv . : .

    [doi:10.1101/2023.01.24.524910]

  • Jenkins L, Jungwirth U, Avgustinova A, Iravani M, Mills AP, Haider S, Harper J and Isacke CM.

    Cancer-Associated Fibroblasts Suppress CD8(+ )T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade

    CANCER RESEARCH . 82(16): 2904-2917. Number of citations: 104

    [doi:10.1158/0008-5472.CAN-21-4141]

  • Gonçalves-Alves E, Garcia-López M, Rodriguez-Hernandez CJ, Gomez-Gonzalez S, Ecker RC, Suñol M, Muñoz-Aznar O, Carcaboso AM, Mora J, Lavarino C and Mateo-Lozano S.

    AC-265347 Inhibits Neuroblastoma Tumor Growth by Induction of Differentiation without Causing Hypocalcemia

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 23(8): 4323. Number of citations: 3

    [doi:10.3390/ijms23084323]