Through this call ERA PerMed aims to foster research on prevention in personalised medicine (PM). Personalised prevention or targeted/tailored prevention considers both individual susceptibility to the risk of disease (e.g. depending on the genomic, environmental background or lifestyle) and its perceived value and benefit (cultural and social factors). Important components of prevention in personalised medicine also include the 1) integration of the patients and citizen's needs, connected to autonomous decision-making, as a factor in the future up-take of preventive interventions by society, and 2) education and reimbursement strategies to allow equal access.

The overall objectives of the ERA PerMed call are to:

• Support translational research projects in the field of personalised medicine;
• Encourage and enable interdisciplinary collaborations towards implementation of PM, in combining pre-clinical or clinical research with bio-informatics components as well as ELSA research or implementation research, including health economics;
• Encourage collaboration between academia (research teams from universities, higher education institutions, public research institutions, research centres), clinical/public health research (research teams from hospital/ public health, healthcare settings and other healthcare organisations), private partners e.g. SMEs (small and medium-sized enterprises) as well as policy makers, regulatory/HTA agencies and patient organisations.

The call is constructed around the following three research areas in order to ensure the development of specific PM approaches considering the major aspects needed for their successful implementation in the health systems:

1. "Translating Basic to Clinical Research and Beyond". Module 1.A-Pre-clinical research; Module 1.B- Clinical research
2. "Data and Information and Communication Technology (ICT)". Module 2A- Enabling Technology; 2B- Towards application in healthcare
3. "Responsible and Effective Implementation in Healthcare". Module 3A- Health economics and Implementation support; Module 3B-Ethical Legand and Social Apsects.

Each research area consists of two modules. Each proposal MUST address at least one module out of each research area.

ERA PerMed strongly encourages the active involvement of members of the public in the proposed research projects.

Joint research proposals may be submitted by applicants belonging to the following categories (subject to regional/national funding regulations):

A. Academia (research teams working in universities, other higher education institutions) or research institutes;

B. Clinical/public health sector (research teams working in hospitals/public health and/or other healthcare settings and health organisations). Participation of clinicians (e.g. medical doctors, nurses) in the research teams is encouraged;

C. Private for-profit (industry) partners, e.g. SME (small and medium-sized enterprises) and private non-profit partners, e.g. foundations, associations or non-governmental organisations.

Whilst applications will be submitted jointly by groups from several countries, individual groups will be funded by the individual ERA PerMed funding organisation respective of the region/country from which applicants have applied. Only transnational projects will be funded. 

Each consortium submitting a proposal must involve at least three partners eligible for funding coming from three different countries whose funding organisations participate to the call (see list below). All three legal entities must be independent from each other. At least two partners out of the minimum three eligible project partners of the consortium must be from two different EU Member States or Associated Countries.

The maximum number of partners per pre-proposal is six though not more than 2 partners from the same country participating in the call will be accepted in one project consortium (including those partners with own funding). At the full-proposal stage, a consortium might be increased up to seven partners in total only by inclusion of a partner coming from an underrepresented country. A list of underrepresented countries will be provided to coordinators invited for full-proposals submission.

It is mandatory to integrate as principle investigator at least one early-career researcher in a consortium.

Only research areas 1 and 2 are eligible for funding. Research area 3 is not eligible for funding.

Due to the complexity of this call, interested PIs are strongly advised to conctact  frecerca.internacional@sjd.es.