Challenge aiming to inspire transformative potential solutions to help or aim to advance precision medicine approaches in immune-mediated diseases.

JLABS periodically launches JLABS QuickFire Challenges. These global challenges support working with local partners for innovation and empower innovative scientists, companies and entrepreneurs to seek comprehensive and integrated solutions that hold the potential of improving the health of people around the world, particularly in areas of significant global impact on people's health. These competitions call for early-stage innovators to apply for a chance to win research grants, access to lab spaces, exposure to the innovation community and other startups, global industry networking opportunities, mentorship and coaching from Johnson & Johnson Innovation and its partners.

Within the framework of the 'Immunology Innovations QuickFire Challenge: Precision Medicine in Immune-Mediated Disease', innovators with transformative potential solutions to help or aim to advance precision medicine approaches in immune-mediated disease are invited to apply.

Innovators with transformative potential solutions to help or aim to advance precision medicine approaches in immune-mediated diseases are invited to apply. This may include:

• Novel approaches toward patient stratification and precision medicine that can be harnessed in immune-mediated diseases including:
  • Multidimensional biomarker discovery platforms, including those with AI/ML based analytics.
  • Deep patient clinical and molecular phenotyping data sets.
  • Novel biomarkers for patient segmentation including digital and imaging biomarkers.
• Novel therapies with clear precision medicine strategy to address a defined patient segment.
• Enabling technologies for clinical trials:
  • Potential solutions aiming to identify and recruit specific patient sub-populations.
  • Potential solutions aiming to resolve technical issues associated with large scale PBMC collection and preparation for multiomics analysis.
  • High dimensional blood immune profiling platforms (e.g., cellular, autoantibodies, complement, proteomics, exosomes, mass spec).
  • Tissue based single cell RNA sequencing.

Specific disease areas of focus for this challenge include gastroenterology, rheumatology, dermatology, fetal-maternal diseases, autoantibody-mediated diseases, and other immune-mediated diseases where a stratified approach has the potential to be transformational for patients.

Potential solutions will be evaluated by a panel of reviewers on their ability to meet the following criteria:

• Uniqueness of the idea.
• Potential impact on human health, with a specific focus on inclusive innovations.
• Feasibility of the idea.
• Thoroughness of approach.
• Identification of key resources and a plan to further the idea.

Eligible applicants are innovators from around the world.

Each Challenge has its own terms & conditions that can be found prior to filling out the application.

Applications may be submitted through the online application system by the deadline of 14 January 2022