Object

The grant funds new research on common mechanisms of autoimmunity to generate new insights for novel therapeutic approaches, by identifying networks and pathways involved in their immune-pathogenesis of diseases, in order to establish immune signatures, biomarkers and targets of effective therapies.

Main Features

All applications must include at least two or more autoimmune disease areas, including at least one of the following autoimmune diseases: Type 1 Diabetes (T1D), Systemic Lupus Erythematosus (SLE) and Multiple Sclerosis (MS). Applications must utilize novel technologies and/or analytical approaches in a multidisciplinary manner. In response to this announcement, LOI’s can be submitted under one of the following mechanisms:

- Strategic Research Agreement (SRA)

- Pilot & Feasibility (PNF)

Requeriments

Applicants must hold an M.D., D.M.D., D.V.M., Ph.D., or equivalent academic degree and hold a faculty position or equivalent at a college, university, medical school, or comparable institution. Applications may be submitted by domestic or foreign non-profit organizations, public or private, such as colleges, universities, hospitals, laboratories, units of state or local governments, or eligible agencies of the federal government, For clinical studies, applicants must hold an appointment or joint appointment in a subspecialty of clinical medicine, and conduct human clinical research.

Projects involving parties with complementary expertise are highly encouraged to submit to this RFA. This may include collaborations between research and clinical groups, science groups with technology experts, and public-private partnerships.
There are no citizenship requirements. To assure continued excellence and diversity among applicants and awardees, this RFA welcomes applications from all qualified individuals and encourages applications from persons with disabilities, women, and members of minority groups underrepresented in the sciences.

Funding

- Strategic Research Agreement (SRA): $750,000

- Pilot & Feasibility (PNF): $200,000

Duration

- Strategic Research Agreement (SRA): up to three years

- Pilot & Feasibility (PNF): up to two years

Documentation

Proposals will follow a 2-step procedure:

- Step 1:Letter of Intent. Deadline, Sept 9, 2019.

- Step 2: Full Application: If the applicant’s LoI is approved by JDRF, the applicant will be invited to submit a full research application.

Both steps are submitted through JDRF's Research Management System (RMS360):

https://jdrf.smartsimple.us/s_Login.jsp

In case of interest, please contact with Research Management Department until 02th September 2019.