People / Staff

Alexandra Avgustinova

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Publications

  • Lorito N, Subbiani A, Smiriglia A, Bacci M, Bonechi F, Tronci L, Romano E, Corrado A, Longo DL, Iozzo M, Ippolito L, Comito G, Giannoni E, Meattini I, Avgustinova A, Chiarugi P, Bachi A and Morandi A.

    FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.

    EMBO Molecular Medicine . 16(7): 1533-1559. Number of citations: 4

    [doi:10.1038/s44321-024-00090-6]

  • Sanchez-Guixe E, Muiños F, Pinheiro-Santin M, González-Huici V, Rodriguez-Hernandez CJ, Avgustinova A, Lavarino C, González- Pérez A, Mora J and López-Bigas N.

    Origins of Second Malignancies in Children and Mutational Footprint of Chemotherapy in Normal Tissues

    CANCER DISCOVERY . 14(6): 953-964. Number of citations: 2

    [doi:10.1158/2159-8290.CD-23-1186]

  • Llorente A, Blasco MT, Espuny I, Guiu M, Ballaré C, Blanco E, Caballé A, Bellmunt A, Salvador F, Morales A, Nuñez M, Loren G, Imbastari F, Fidalgo M, Figueras-Puig C, Gibler P, Graupera M, Monteiro F, Riera A, Holen I, Avgustinova A, Di Croce L and Gomis RR.

    MAF amplification licenses ERa through epigenetic remodelling to drive breast cancer metastasis

    NATURE CELL BIOLOGY . : 1833-1847.

    [doi:10.1038/s41556-023-01281-y]

  • Figuerola-Bou E, Rios-Astorch C, Blanco E, Sanchez-Jimenez M, Táboas-Outón P, Fernandez-Isern G, Gomez-Gonzalez S, Muñoz-Aznar O, Castellano P, Pérez-Jaume S, Prada-Varela E, Mateo-Lozano S, Riggi N, Avgustinova A, Lavarino C, Di Croce L, Sánchez-Molina S and Mora J.

    KDM6 demethylases mediate EWSR1-FLI1-driven oncogenic transformation in Ewing Sarcoma

    Biorxiv . : .

    [doi:10.1101/2023.01.24.524910]

  • Jenkins L, Jungwirth U, Avgustinova A, Iravani M, Mills AP, Haider S, Harper J and Isacke CM.

    Cancer-Associated Fibroblasts Suppress CD8(+ )T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade

    CANCER RESEARCH . 82(16): 2904-2917. Number of citations: 101

    [doi:10.1158/0008-5472.CAN-21-4141]

  • Avgustinova A, Laudanna C, Pascual-García M, Rovira Q, Djurec M, Castellanos A, Urdiroz-Urricelqui U, Marchese D, Prats N, Van Keymeulen A, Heyn H, Vaquerizas JM and Benitah SA.

    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development.

    Cell stem cell . 28(10): 1790. Number of citations: 7

    [doi:10.1016/j.stem.2021.04.030]

  • Avgustinova A, Symeonidi A, Castellanos A, Urdiroz-Urricelqui U, Solé-Boldo L, Martín M, Pérez-Rodríguez I, Prats N, Lehner B, Supek F and Benitah SA.

    Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.

    NATURE CELL BIOLOGY . 20(12): 1400-1409. Number of citations: 29

    [doi:10.1038/s41556-018-0233-x]

  • Li H, Yao Q, Mariscal AG, Wu X, Hülse J, Pedersen E, Helin K, Waisman A, Vinkel C, Thomsen SF, Avgustinova A, Benitah SA, Lovato P, Norsgaard H, Mortensen MS, Veng L, Rozell B and Brakebusch C.

    Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.

    NATURE COMMUNICATIONS . 9(1): 1420-1420. Number of citations: 92

    [doi:10.1038/s41467-018-03704-z]

  • Rinaldi L, Avgustinova A, Martín M, Datta D, Solanas G, Prats N and Aznar Benitah S.

    Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-?.

    eLife . 6: . Number of citations: 42

    [doi:10.7554/eLife.21697]

  • Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L and Aznar Benitah S.

    Targeting metastasis-initiating cells through the fatty acid receptor CD36.

    Nature . 541(7635): 41-45. Number of citations: 931

    [doi:10.1038/nature20791]