Mónica Roldan Molina
Investigador
Research group
Research line:
Advanced microscopy technologies applied to the diagnosis of rare diseases
Researcher Mònica Roldán graduated in Biology in 1996 from the Autonomous University of Barcelona. In 2000, she completed an Experimental Master in Pharmaceutical Sciences and in 2003 she received the Advanced Studies Diploma in the framework of the Medicines, Food and Health program at the University of Barcelona. In 2008 she received his Doctor of Biology degree (Cum Laude and Extraordinary Award) from the same university.
His professional experience in the field of advanced microscopy technologies goes back to 2006 when I obtained a position at the Autonomous University of Barcelona as head of the Confocal Microscopy Unit of the Central Scientific and Technical Services. During 2007 she spent a stint at LAMBS- MicroScoBio, Laboratory for Advanced Microscopy Bioimaging Spectroscopy at the University of Genoa, where she studied multiphoton microscopy techniques and F. She has been an associate professor at the University of Barcelona and has given internships in various bachelor's and master's degrees in the field of biology at the Autonomous University of Barcelona. She is currently an Associate Professor at the Polytechnic University of Catalonia. During his career she has directed a doctoral dissertation at the University of Barcelona and six master's theses at the Autonomous University of Barcelona.
From 2005 to 2017 she has been the coordinator of the Leica Confocal Microscopy Training Center and is currently conducting confocal microscopy training and advanced fluorescence technologies for researchers from all over Spain. Since 2010 she has been teaching at different microscopy centers in Costa Rica and Mexico (Universidad de Costa Rica, Universidad Autónoma Metropolitana de México, Centro de Investigación y de Estudios Avanzados of the National Polytechnic Institute of Mexico and INECOL). She is the author of more than 40 scientific articles in the field of these technologies.
In 2017 she joins the Leader of the Newly created Confocal Microscopy and Superresolution Unit at the Pediatric Institute for Rare Diseases of the Sant Joan de Déu Hospital. This unit is located at the Pathological Anatomy Service and has a care and research aspect. She is currently working on a number of projects, including the diagnosis of rare diseases, which involves the development of unique methods that combine advanced microscopy technologies and image analysis with artificial intelligence to develop new diagnostic tools. In this context, she is working on diagnostic methods for serious diseases, such as Duchenne-Becker muscular dystrophy, Ullrich and Bethlem's myopathies, and mitochondrial diseases, as well as hematological diseases such as thalassemia.
Last Publications
- Mora J, Climent A, Roldan-Molina M, Flores MC, Varo A, Pérez-Jaume S, Jou-Munoz C, Celma MS, Lazaro JJ, Cheung I, Castañeda-Heredia A, Gorostegui M, Rodriguez E, Chamorro S, Muñoz JP and Cheung NK Desensitizing the autonomic nervous system to mitigate anti-GD2 monoclonal antibody side effects Frontiers in oncology . 14: 1380917-1380917.
- Roldan-Molina M, Nolasco-Tovar GA, Armengol L, Frías M, Morell M, García-Aragonés M, Epifani F, Muchart-Lopez J, Ramírez-Almaraz ML, Martorell-Sampol L, Hernando-Davalillo C, Urreizti R and Serrano M Advanced Optical Microscopy: Unveiling Functional Insights Regarding a Novel PPP2R1A Variant and Its Unreported Phenotype INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 24(18): .
- Badosa-Gallego MC, Roldan-Molina M, Fernández-Irigoyen J, Santamaria E and Jimenez-Mallebrera C Proteomic and functional characterisation of extracellular vesicles from collagen VI deficient human fibroblasts reveals a role in cell motility SCIENTIFIC REPORTS . 13(1): 14622-14622.
Projects
- Project name:
- Identificació no invasiva i precoç mitjançant espectroscòpia Raman del retinoblastoma
- Leader
- Mónica Roldan Molina, Maria Suñol Capella
- Funding entities:
- Fundació La Nineta dels Ulls
- Code
- PFNR0202
- Starting - finishing date:
- 2024 - 2024
- Project name:
- BE-LIGHT: Improving BiomEdical diagnosis through LIGHT-based technologies and machine learning
- Leader
- Mónica Roldan Molina
- Funding entities:
- European Commission
- Code
- 101119924
- Starting - finishing date:
- 2023 - 2026
- Project name:
- Cerrando la brecha terapeutica para Distrofias Musculares Congenitas. Estrategias para mejorar la eficacia, liberacion y seguridad de terapias basadas en CRISPR/Cas9 y oligonucleotidos
- Leader
- Cecilia Jiménez Mallebrera
- Funding entities:
- Instituto de Salud Carlos III (ISCIII), Fundació Privada per a la Recerca i la Docència Sant Joan de Déu - FSJD, Jiménez Mallebrera, Cecilia
- Code
- PI22/01382
- Starting - finishing date:
- 2023 - 2025
News
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Characterization of Extracellular Vesicles in Fibroblasts of Collagen-VI Related Muscular Dystrophy
A team led by the Applied research in neuromuscular diseases at the Institut de Recerca Sant Joan de Déu · SJD Barcelona Children's Hospital has made significant advancements in comprehending the pathogenesis of Collagen-VI Related Muscular Dystrophy (COL6-RD) by analyzing extracellular vesicles and their correlation with cellular mobility.
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Gene therapy proved against Muscular Distrophy with the ALBA Synchrotron
A study by the Institut de Recerca Sant Joan de Déu, ICFO, CIBERER and the ALBA Synchrotron has helped demonstrate that gene therapy can reverse the effects of the mutation that causes the symptoms of congenital muscular dystrophy in patient cells.
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Institut de Recerca Sant Joan de Déu and ICFO create a joint lab to improve neonatal and paediatric health care
The new joint laboratory will advance the use and development of photonic technologies to understand, diagnose, monitor and treat paediatric diseases.